Pilot Data Reveals Red Wine Polyphenols, Vitamin E & Zinc May Enhance Muscular Regeneration

A new pilot study that was recently carried out by Seppic has shown that using a combination of red wine polyphenols, vitamin E, and Zinc for 12 days could inhibit the process of muscle damage while maintaining healthy men’s general muscular power.

Interestingly, scientists report that they have discovered the significant value of using a branded ingredient of Seppic’s Specifit Protect. According to the researchers, they found that doing this led to significantly reduced creatine kinase levels, when compared to placebo. The scholars determined this following a unique protocol organized to manage pain induction. The same procedure is commonly used to simulate the physical exertion process.

Furthermore, the various participants in the placebo class significantly displayed significant reductions in the overall capacity of muscular power. Such dramatic declines were, however, not observed in either the SPro or the Sepifit Protect group. These remarkable results come from information that was published recently in the respected NutraFoods journal. Christine Garcia and Katherine Kern who are both Seppic’s staffers currently working in France, wrote:

“From the users’ standpoint, and considering performance matters, the virility of SPro was considered to be stronger than a placebo, muscle soreness sensations, and the general physical state. Interestingly, these results corroborate past in vitro data, which highlighted SPro as being a highly promising muscle protection active complex, particularly during those moments of intense physical exertion.”

The ingredients

Notably, Sepifit Protect was launched by SEPPIC back in 2016. A company spokesman recently said this to the NutraIngredients-USA journal:

“Our ‘soft launch’ came as the answer to our customers’ interests. Yes, it is true that, at first, we prioritized issues of commercial interest as well as success; we had plans to steer the pilot study revolving around the placebo in such a way that it would come out as a complete product with proven efficacy. It is, therefore, with much excitement that we would like to announce the results of our clinical trials. We hope that this will offer a new wellness brand as well as a robust science- to- sports nutrition. Moreover, in the future, we hope to advance more science across various ingredients. This will, likely, boost our objective to continue promoting high standards as we inject innovation to the entire industry.”

The Details

The process that led to the above results was relatively simple. Kern and Garcia engaged a group of 30 healthy men to take part in the pilot study. These ranged from between 18 and 40 years of age. All the subjects were asked to exercise regularly for three months. They did this every week for 1.5 to 4.5 hours. The study group were randomly allocated 135 mg of zinc, red wine polyphenols, and maltodextrin (placebo) or vitamin E combination for 12 days.

At the beginning and end of this study, all the subjects filled a special questionnaire for the International Physical Activity. This is a short, IPAQ-SF Form. 29 of the participants were successful and completed the study. The study protocol included two special exercises; several drop jumps or down-below-jumps, and a series of 40 cm, little-hurdle-jumps.

As a result, the creatine kinase or (CK) levels for the active group had dropped to 70% lower when compared to the placebo. In particular, the levels of CK for the active group had increased by 10.5 IU for each litter. This compares to a 35.7 IU /litter in the group using a placebo.

Furthermore, Garcia and Ken reported a 1.1 cm decrease of muscular power in the group linked to the Sepifit Protect, which compared to a 2.3 cm decrease in the placebo group. They added,

“This data represents a 52% less reduction in the active group when compared to the other; the placebo group. Overall, the difference noted between these groups can be said to be p=0.086. This represents a borderline significance.”

The IPAQ-SF data also indicated an improved physical condition and perception of performance in the Sepifit Protect category, as well as some muscle soreness. The researchers wrote,

“Such results give credence to the previous data gathered in vitro and isolate SepiFit Protect as a complex carrying the promise for enhanced muscle regeneration following a period of physical activity. This would, therefore, help to maintain a general performance as well as physical activity.”

The researchers, however, conclude thus:

“There is a need for further confirmation in clinical studies involving an expanded group of subjects as well as enhanced kinetic measurement to corroborate everything.”